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Link rowid title DOI URL created subject ▼ references-count is-referenced-by-count ISSN container-title abstract author_number orcids names award_numbers funder_names funder_dois
78 ["Construction of the secondary care administrative records frailty (SCARF) index and validation on older women with operable invasive breast cancer in England and Wales: a cohort study"] 10.1136/bmjopen-2019-035395 http://dx.doi.org/10.1136/bmjopen-2019-035395 2020-05-06T10:36:50Z ["General Medicine"] 48 0 ["2044-6055", "2044-6055"] BMJ Open <jats:sec><jats:title>Objectives</jats:title><jats:p>Studies that use national datasets to evaluate the management of older women with breast cancer are often constrained by a lack of information on patient fitness. This study constructed a frailty index for use with secondary care administrative records and evaluated its ability to improve models of treatment patterns and overall survival in women with breast cancer.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Retrospective cohort study.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>Women aged ≥50 years with oestrogen receptor (ER) positive early invasive breast cancer diagnosed between 2014 and 2017 in England.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The secondary care administrative records frailty (SCARF) index was based on the cumulative deficit model of frailty, using International Statistical Classification of Diseases, Injuries and Causes of Death, 10th revision codes to define a set of deficits. The index was applied to administrative records that were linked to national cancer registry datasets. The ability of the SCARF index to improve the performance of regression models to explain observed variation in the rate of surgery and overall survival was evaluated using Harrell’s c-statistic and decision curve analysis. External validation was performed on a dataset of similar women diagnosed in Wales.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The SCARF index captured 32 deficits that cover functional impairment, geriatric syndromes, problems with nutrition, cognition and mood, and medical comorbidities. In the English dataset (n=67 925), the prevalence of frailty in women aged 50–69, 70–79 and ≥80 years was 15%, 28% and 47%, respectively. Adding a frailty measure to regression models containing age, tumour characteristics and comorbidity improved their ability to: (1) discriminate between whether a woman was likely to have surgery and (2) predict over… 11 ["http://orcid.org/0000-0002-4761-8655"] ["Yasmin Jauhari", "Melissa Ruth Gannon", "David Dodwell", "Kieran Horgan", "Karen Clements", "Jibby Medina", "Carmen Tsang", "Thompson Robinson", "Sarah Shuk-Kay Tang", "Ruth Pettengell", "David A Cromwell"] [] ["Healthcare Quality Improvement Partnership"] [[""]]
84 ["How far are we from a medication use process aiming at well-informed adherent patients with long-term medications in Finland? Qualitative study"] 10.1136/bmjopen-2019-036526 http://dx.doi.org/10.1136/bmjopen-2019-036526 2020-06-22T07:06:08Z ["General Medicine"] 72 0 ["2044-6055", "2044-6055"] BMJ Open <jats:sec><jats:title>Objective</jats:title><jats:p>Finland is one of the few countries that has established a national Medicines Information (MI) Strategy. The ultimate goal of the strategy is a well-implemented medication use process resulting in well-informed adherent patients. This study aimed at evaluating the implementation of the strategy 3 years after its launch.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>The evaluation applied a pragmatic approach and was conducted by interviewing stakeholders involved in the National MI Network enhancing the MI Strategy’s implementation. The network comprises national key stakeholders producing and using MI. Data were deductively analysed according to the medication use process of the MI Strategy using the framework method, complemented with inductively derived categories.</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>National implementation of the MI Strategy throughout the healthcare system after the first operational period (2012–2014) in 2015.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>The members of the National MI Network (n=79/111, participation rate 71%, representing 42/53 stakeholder organisations).</jats:p></jats:sec><jats:sec><jats:title>Outcome measures</jats:title><jats:p>A new conceptual framework was developed based on stakeholders’ views on well-implemented actions and actions needing development in the medication use process at (1) infrastructure (<jats:italic>macro</jats:italic>), (2) healthcare professionals (<jats:italic>meso</jats:italic>) and (3) patient (<jats:italic>micro</jats:italic>) levels.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Medication counselling by community pharmacists was the primary implemented action, followed by physicians’ actions while starting a new medication, and advice given by nurses. The major development needs concerned (1) poor access to patient information and its transfer in healthcare, particularly the lack of r… 4 ["http://orcid.org/0000-0001-7846-3492"] ["Niina Mononen", "Marika Pohjanoksa-M\u00e4ntyl\u00e4", "Marja SA Airaksinen", "Katri H\u00e4meen-Anttila"] [] ["Elli Turunen Fund of the Finnish Cultural Foundation"] [[""]]
79 ["Processes and contexts influencing health inequalities among women who are mothers"] 10.1136/jech-2019-212229 http://dx.doi.org/10.1136/jech-2019-212229 2019-06-10T21:19:16Z ["Public Health, Environmental and Occupational Health", "Epidemiology"] 20 0 ["0143-005X", "1470-2738"] Journal of Epidemiology and Community Health <jats:p>This paper presents a conceptual framework that aims to conceptualise the different processes and contexts influencing health inequalities among women who are mothers. On the one hand, four processes are shown: (1) social stratification; (2) route into motherhood; (3) exposure and vulnerability to risk factors; and (4) generation of health inequalities. On the other hand, the role of the socioeconomic and political context, the labour market context, and the social, community and family context, as well as their inter-relationships, are presented. In addition, different family policy models, social values and cultural imperatives are considered.</jats:p> 5 ["http://orcid.org/0000-0001-6653-3393", "http://orcid.org/0000-0002-1170-2505"] ["Sara Trujillo-Alem\u00e1n", "Gloria Perez", "Jillian Reynolds", "Silvia Rueda", "Carme Borrell"] ["278173-2"] ["SOPHIE Project - Evaluating the Impact of Structural Policies on Health Inequalities and their Social Determinants and Fostering Change"] [[""]]
18 ["Post-traumatic growth and its relationship to quality of life up to 9 years after liver transplantation: a cross-sectional study in Spain"] 10.1136/bmjopen-2017-017455 http://dx.doi.org/10.1136/bmjopen-2017-017455 2017-09-17T00:10:22Z [] 0 7 ["2044-6055", "2044-6055"] BMJ Open <jats:sec><jats:title>Objective</jats:title><jats:p>Little is known concerning post-traumatic growth (PTG) after liver transplantation. Against this backdrop the current study analysed the relationship between PTG and time since transplantation on quality of life. Furthermore, it compared PTG between liver transplant recipients and their caregivers.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Cross-sectional case–control study.</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>University Hospital in Spain.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>240 adult liver transplant recipients who had undergone only one transplantation, with no severe mental disease, were the participants of the study. Specific additional analyses were conducted on the subset of 216 participants for whom caregiver data were available. Moreover, results were compared with a previously recruited general population sample.</jats:p></jats:sec><jats:sec><jats:title>Outcome measures</jats:title><jats:p>All participants completed the Posttraumatic Growth Inventory, and recipients also filled in the 12-Item Short-Form Health Survey. Relevant sociodemographic and clinical parameters were also assessed.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>In the sample of 240 recipients, longer time since transplantation (&gt;9 years) was associated with more pain symptoms (p=0.026). Regardless of duration, recipients showed lower scores on most quality of life dimensions than the general population. However, high PTG was associated with a significantly higher score on the vitality quality of life dimension (p=0.021). In recipients with high PTG, specific quality of life dimensions, such as bodily pain (p=0.307), vitality (p=0.890) and mental health (p=0.353), even equalled scores in the general population, whereas scores on general health surpassed them (p=0.006). Furthermore, liver transplant recipients (n=216) compared with their caregivers showed higher t… 7 [] ["Mar\u00eda \u00c1ngeles P\u00e9rez-San-Gregorio", "Agust\u00edn Mart\u00edn-Rodr\u00edguez", "Mercedes Borda-Mas", "Mar\u00eda Luisa Avargues-Navarro", "Jos\u00e9 P\u00e9rez-Bernal", "Rupert Conrad", "Miguel \u00c1ngel G\u00f3mez-Bravo"] [] ["Spanish Ministry of Economy and Competitiveness"] [[""]]

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   [title] TEXT,
   [DOI] TEXT,
   [URL] TEXT,
   [created] TEXT,
   [subject] TEXT,
   [references-count] TEXT,
   [is-referenced-by-count] TEXT,
   [ISSN] TEXT,
   [container-title] TEXT,
   [abstract] TEXT,
   [author_number] TEXT,
   [orcids] TEXT,
   [names] TEXT,
   [award_numbers] TEXT,
   [funder_names] TEXT,
   [funder_dois] TEXT
);