3 rows where is-referenced-by-count = 4 sorted by is-referenced-by-count

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Link rowid title DOI URL created subject references-count is-referenced-by-count ▼ ISSN container-title abstract author_number orcids names award_numbers funder_names funder_dois
26 ["Relationship between estimated cardiovascular disease risk and insulin resistance in a black African population living with HIV: a cross-sectional study from Cameroon"] 10.1136/bmjopen-2017-016835 http://dx.doi.org/10.1136/bmjopen-2017-016835 2017-08-11T20:25:24Z [] 0 4 ["2044-6055", "2044-6055"] BMJ Open <jats:sec><jats:title>Objectives</jats:title><jats:p>Cardiovascular disease (CVD) and metabolic diseases are growing concerns among patients with HIV infection as a consequence of the improving survival of this population. We aimed to assess the relationship between CVD risk and insulin resistance in a group of black African individuals with HIV infection.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>This cross-sectional study involved patients with HIV infection aged 30–74 years and followed up at the Yaoundé Central Hospital, Cameroon. Absolute CVD risk was calculated using the Framingham and the DAD CVD risk equations while the HOMA-IR index was used to assess insulin resistance (index ≥2.1).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>A total of 452 patients (361 women; 80%) were screened. The mean age was 44.4 years and most of the respondents were on antiretroviral therapy (88.5%). The median 5-year cardiovascular risk was 0.7% (25th−75th percentiles: 0.2–2.0) and 0.6% (0.3–1.3) according to the Framingham and DAD equations respectively. Of all participants, 47.3% were insulin resistant. The Framingham equation derived absolute CVD risk was significantly associated with insulin resistance; while no linear association was found using the DAD equation.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>The relationship between cardiovascular risk and insulin resistance in black African patients with HIV infection seems to depend on the cardiovascular risk equation used.</jats:p></jats:sec> 13 ["http://orcid.org/0000-0001-8018-6279", "http://orcid.org/0000-0001-6155-235X"] ["Steve Raoul Noumegni", "Jean Joel Bigna", "Vicky Jocelyne Ama Moor epse Nkegoum", "Jobert Richie Nansseu", "Felix K Assah", "Ahmadou Musa Jingi", "Magellan Guewo-Fokeng", "Steve Leumi", "Jean-Claude Katte", "Mesmin Y Dehayem", "Liliane Mfeukeu Kuate", "Andre Pascal Kengne", "Eugene Sobngwi"] [""] [""] [""]
27 ["Guideline review: British Society of Gastroenterology/UK-PBC Primary Biliary Cholangitis treatment and management guidelines"] 10.1136/flgastro-2018-101109 http://dx.doi.org/10.1136/flgastro-2018-101109 2019-01-09T22:19:25Z [] 11 4 ["2041-4137", "2041-4145"] Frontline Gastroenterology <jats:p>New guidelines have been produced for the management of primary biliary cholangitis, an infrequent but nonetheless important autoimmune liver disease. We provide a succient commentary and overview of the key features of disease management that arise from these recent guideline recommendations, with a focus on therapy with licensed agents (ursodeoxycholic acid and obeticholic acid) as well as personalised management of disease complications and associated symptoms.</jats:p> 2 ["http://orcid.org/0000-0002-6054-569X"] ["Jorn C Goet", "Gideon M Hirschfield"] [""] [""] [""]
28 ["GCAT|Genomes for life: a prospective cohort study of the genomes of Catalonia"] 10.1136/bmjopen-2017-018324 http://dx.doi.org/10.1136/bmjopen-2017-018324 2018-03-28T06:10:36Z [] 0 4 ["2044-6055", "2044-6055"] BMJ Open <jats:sec><jats:title>Purpose</jats:title><jats:p>The prevalence of chronic non-communicable diseases (NCDs) is increasing worldwide. NCDs are the leading cause of both morbidity and mortality, and it is estimated that by 2030, they will be responsible for 80% of deaths across the world. The Genomes for Life (GCAT) project is a long-term prospective cohort study that was designed to integrate and assess the role of epidemiological, genomic and epigenomic factors in the development of major chronic diseases in Catalonia, a north-east region of Spain.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>At the end of 2017, the GCAT Study will have recruited 20 000 participants aged 40–65 years. Participants who agreed to take part in the study completed a self-administered computer-driven questionnaire, and underwent blood pressure, cardiac frequency and anthropometry measurements. For each participant, blood plasma, blood serum and white blood cells are collected at baseline. The GCAT Study has access to the electronic health records of the Catalan Public Healthcare System. Participants will be followed biannually at least 20 years after recruitment.</jats:p></jats:sec><jats:sec><jats:title>Findings to date</jats:title><jats:p>Among all GCAT participants, 59.2% are women and 83.3% of the cohort identified themselves as Caucasian/white. More than half of the participants have higher education levels, 72.2% are current workers and 42.1% are classified as overweight (body mass index ≥25 and &lt;30 kg/m<jats:sup>2</jats:sup>). We have genotyped 5459 participants, of which 5000 have metabolome data. Further, the whole genome of 808 participants will be sequenced by the end of 2017.</jats:p></jats:sec><jats:sec><jats:title>Future plans</jats:title><jats:p>The first follow-up study started in December 2017 and will end by March 2018. Residences of all subjects will be geocoded during the following year. Several genomic analyses are ongoing, and metabolomic and genomic integrations will be performed t… 13 ["http://orcid.org/0000-0003-4646-3513"] ["Mireia Ob\u00f3n-Santacana", "Mireia Vilardell", "Anna Carreras", "Xavier Duran", "Juan Velasco", "Iv\u00e1n Galv\u00e1n-Femen\u00eda", "Teresa Alonso", "Llu\u00eds Puig", "Lauro Sumoy", "Eric J Duell", "Manuel Perucho", "Victor Moreno", "Rafael de Cid"] [] ["\u2019Ram\u00f3n y Cajal' action from the Spanish Ministry of Economy and Competitiveness", "Ag\u00e8ncia de Gesti\u00f3 d\u2019Ajuts Universitaris i de Recerca (AGAUR)", "Acci\u00f3n de Dinamizaci\u00f3n del ISCIII-MINECO", "Ministry of Health of the Generalitat of Catalunya", "the Catalan Government DURSI"] [[""], [""], [""], [""], [""]]

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CREATE TABLE [article] (
   [title] TEXT,
   [DOI] TEXT,
   [URL] TEXT,
   [created] TEXT,
   [subject] TEXT,
   [references-count] TEXT,
   [is-referenced-by-count] TEXT,
   [ISSN] TEXT,
   [container-title] TEXT,
   [abstract] TEXT,
   [author_number] TEXT,
   [orcids] TEXT,
   [names] TEXT,
   [award_numbers] TEXT,
   [funder_names] TEXT,
   [funder_dois] TEXT
);