2 rows where "created" is on date 2019-12-03 sorted by URL

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  • 2019-12-03 · 2
Link rowid title DOI URL ▼ created subject references-count is-referenced-by-count ISSN container-title abstract author_number orcids names award_numbers funder_names funder_dois
66 ["Uptake of routine viral load testing among people living with HIV and its implementation challenges in Yangon region of Myanmar: a mixed-methods study"] 10.1136/bmjopen-2019-032678 http://dx.doi.org/10.1136/bmjopen-2019-032678 2019-12-03T15:46:41Z ["General Medicine"] 29 0 ["2044-6055", "2044-6055"] BMJ Open <jats:sec><jats:title>Objectives</jats:title><jats:p>In 2017, Myanmar implemented routine viral load (VL) monitoring for assessing the response to antiretroviral therapy (ART) among people living with HIV (PLHIV). The performance of routine VL testing and implementation challenges has not yet assessed. We aimed to determine the uptake of VL testing and factors associated with it among PLHIV initiated on ART during 2017 in ART clinics of Yangon region and to explore the implementation challenges as perceived by the healthcare providers.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>An explanatory mixed-methods study was conducted. The quantitative component was a cohort study, and the qualitative part was a descriptive study with in-depth interviews.</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>Six ART clinics operated by AIDS/sexually transmitted infection teams under the National AIDS Programme.</jats:p></jats:sec><jats:sec><jats:title>Primary outcome measures</jats:title><jats:p>(1) The proportion who underwent VL testing by 30 March 2019 and the proportion with virological suppression (plasma VL &lt;1000 copies/mL); (2) association between patient characteristics and ‘not tested’ was assessed using log binomial regression and (3) qualitative codes on implementation challenges.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Of the 567 PLHIV started on ART, 498 (87.8%) retained in care for more than 6 months and were eligible for VL testing. 288 (57.8%, 95% CI: 53.3% to 62.2%) PLHIV underwent VL testing, of which 263 (91.3%, 95% CI: 87.1% to 94.4%) had virological suppression. PLHIV with WHO clinical stage 4 had significantly higher rates of ‘not being tested’ for VL. Collection of sample for VL testing only twice a month, difficulties in sample collection and transportation, limited trained workforce, wage loss and out-of-pocket expenditure for patients due to added visits were major implementation challenges.</jats:p></jats:sec><jats:sec><jats… 8 [] ["Khine Khine Thinn", "Pruthu Thekkur", "Nang Thu Thu Kyaw", "Nyein Su Aye", "Tin Maung Zaw", "Pyae Soan", "San Hone", "Htun Nyunt Oo"] [""] [""] [""]
56 ["High-grade astrocytoma with ventricular invasion in a dog"] 10.1136/vetreccr-2019-000958 http://dx.doi.org/10.1136/vetreccr-2019-000958 2019-12-03T10:42:48Z ["General Veterinary"] 22 0 ["2052-6121"] Veterinary Record Case Reports <jats:p>A 13-year-old female German Shepherd dog was euthanised and submitted to necropsy after a 7-month history of prolonged recumbency and vocalisation. Gross anatomical changes consisted of a well-demarcated, 3.5×1.5 cm, soft red mass that effaced the right lateral ventricle and compressed the adjacent neuroparenchyma. Histologically, elongate neoplastic cells with astrocytic morphology were arranged in short bundles and streams supported by a neuropil-like stroma. Neoplastic cells were immunopositive for glial fibrillar acidic protein (GFAP) and oligodendrocyte transcription factor 2 (Olig2), and immunonegative for e-cadherin and pancytokeratin. Histological and immunohistochemical features were consistent with a high-grade astrocytoma with ventricular invasion, a rare feature of astrocytic tumours in dogs.</jats:p> 5 ["http://orcid.org/0000-0002-7128-8756"] ["Rayane Chitolina Pupin", "Daniel R Rissi", "Danilo Carloto Gomes", "Amanda Gimelli", "Mariana Isa Poci Palumbo"] [""] [""] [""]

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   [DOI] TEXT,
   [URL] TEXT,
   [created] TEXT,
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